Froger 2014 It does not appear to be destroyed through cooking. Taurine is an organic acid that occurs naturally in food, especially in shellfish (eg, scallops, mussels, clams) and in the dark meat of turkey and chicken, as well as in other meats and eggs. Related/similar drugs turmeric, Ginkgo Biloba, echinacea Source Information regarding the safety of long-term taurine supplementation is lacking. A proposed safe level of taurine consumption is 3 g/day however, taurine has been tested in doses as high as 10 g/day for 6 months. ToxicologyĬardiovascular events have been reported following excessive consumption of energy drinks however, it is difficult to attribute these events directly to taurine because the drinks contain multiple ingredients and energy drink consumption is often accompanied by excessive alcohol intake or physical activity. No adverse events have been noted for dosages up to 3 g/day. Taurine inhibits cytochrome P450 (CYP-450) 2E1, and any drugs that are substrates of this isoenzyme may be impacted with coadministration. It is also an ingredient in many baby formulas. It may be protective against neural tube defects. Taurine passes to the developing fetus through maternal circulation during pregnancy and to the newborn via breast milk. Information regarding supplementation above normal requirements is lacking, and caution is warranted. ContraindicationsĬontraindications have not been identified. Portal hypertension: Taurine 6 g/day for 1 month. Hypertension: Supplemental taurine 3 to 6 g/day (treatment duration range, 1 to 8 weeks). Exercise: Various dosages and treatment durations of taurine, either alone or as part of a combination energy product, have been evaluated for effects on exercise. Chronic hepatitis: Taurine 2 g 3 times daily for 3 months. Taurine has been studied in doses of 1 to 6 g/day. Large quality clinical trials that might establish a definitive place for taurine in therapy are lacking, and results from animal studies have yet to be translated to the clinical setting. Supplemental taurine has been evaluated for use in cardiovascular conditions and diabetes, and for its CNS effects. Common Name(s): 2-aminoethanesulfonic acid, Bos taurus, Tau, Taurine
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